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DIABLO anticorps
DIABLO
Reactivité: Humain, Souris
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2422157
Détail du produit anti-DIABLO anticorps
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Antigène
Voir toutes DIABLO Anticorps
DIABLO
(Second Mitochondria-Derived Activator of Caspase (DIABLO))
Reactivité
Toutes les réactivités sur DIABLO Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur DIABLO Anticorps
Lapin
Clonalité
Toutes les clonalités sur DIABLO Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers DIABLO Anticorps
Cet anticorp DIABLO est non-conjugé
Application
Tous les applications à travers DIABLO Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Purification
Affinity purification
Immunogène
Recombinant protein of human DIABLO
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
WB 1:1000-1:5000, IHC 1:100-1:300
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Conseil sur la manipulation
Avoid freeze / thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur DIABLO
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Antigène
DIABLO
(Second Mitochondria-Derived Activator of Caspase (DIABLO))
Autre désignation
DIABLO (DIABLO Produits )
Synonymes
anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L
Sujet
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed.
Poids moléculaire
Calculated MW: 27 kDa
Pathways
Apoptose , Caspase Cascade in Apoptosis , Positive Regulation of Endopeptidase Activity
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