PIM2 anticorps

N° du produit ABIN2422823

Détail du produit anti-PIM2 anticorps

Antigène: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogène: Recombinant protein of human PIM2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PIM2

Antigène: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Autre désignation: PIM2 (PIM2 Produits)

Synonymes: anticorps cb1068, anticorps fj47b05, anticorps pim2, anticorps wu:fj47b05, anticorps DXCch3, anticorps Pim-2, anticorps Pim-2 proto-oncogene, serine/threonine kinase, anticorps proviral integration site 2, anticorps pim2, anticorps PIM2, anticorps Pim2

Sujet: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.