BRE anticorps
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- Antigène Voir toutes BRE Anticorps
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BRE est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human BRE
- Isotype
- IgG
- Top Product
- Discover our top product BRE Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Conseil sur la manipulation
- Avoid freeze / thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
- Autre désignation
- BABAM2 (BRE Produits)
- Synonymes
- anticorps brcc4, anticorps brcc45, anticorps BRE, anticorps LOC100231620, anticorps BRCC4, anticorps BRCC45, anticorps 6030405P19Rik, anticorps AI429776, anticorps B830038C02Rik, anticorps im:7141046, anticorps zgc:110368, anticorps BRISC and BRCA1 A complex member 2, anticorps brain and reproductive organ-expressed (TNFRSF1A modulator), anticorps BRISC and BRCA1 A complex member 2 L homeolog, anticorps babam2, anticorps BABAM2, anticorps Babam2, anticorps BRE, anticorps babam2.L
- Sujet
- Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
- Poids moléculaire
- Calculated MW: 44 kDa
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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