Apoptosis Inhibitor 5 anticorps

N° du produit ABIN2426083

Détail du produit anti-Apoptosis Inhibitor 5 anticorps

Antigène: Apoptosis Inhibitor 5 (API5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Apoptosis Inhibitor 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogène: Synthetic peptide of human API5

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Apoptosis Inhibitor 5

Antigène: Apoptosis Inhibitor 5 (API5)

Autre désignation: API5 (API5 Produits)

Synonymes: anticorps AAC-11, anticorps AAC11, anticorps AI196452, anticorps api5l1, anticorps sr:nyz021, anticorps zgc:66211, anticorps wu:fb26c03, anticorps API-5B, anticorps aac-11, anticorps aac11, anticorps api5, anticorps API-5A, anticorps api5-A, anticorps MGC83290, anticorps API5, anticorps apoptosis inhibitor 5, anticorps apoptosis inhibitor 5 S homeolog, anticorps apoptosis inhibitor 5 L homeolog, anticorps API5, anticorps Api5, anticorps api5, anticorps api5.S, anticorps api5.L

Sujet: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: Calculated MW: 57 kDa

NCBI Accession: NP_006586

Pathways: Growth Factor Binding