SLC22A17 anticorps

N° du produit ABIN2426895

Détail du produit anti-SLC22A17 anticorps

Antigène: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A17 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Synthetic peptide of human SLC22A17

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLC22A17

Antigène: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Autre désignation: SLC22A17 (SLC22A17 Produits)

Synonymes: anticorps 1700094C23Rik, anticorps 24p3R, anticorps AU041908, anticorps AW555662, anticorps BOIT, anticorps Boct, anticorps mBOCT, anticorps BOCT, anticorps NGALR, anticorps NGALR2, anticorps NGALR3, anticorps hBOIT, anticorps rBOCT, anticorps solute carrier family 22 member 17, anticorps solute carrier family 22 (organic cation transporter), member 17, anticorps solute carrier family 22, member 17, anticorps SLC22A17, anticorps Slc22a17

Sujet: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

NCBI Accession: NP_065105

Pathways: Transition Metal Ion Homeostasis