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FZD6 anticorps

FZD6 Reactivité: Humain, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2427013
  • Antigène Voir toutes FZD6 Anticorps
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Reactivité
    • 37
    • 14
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 38
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 41
    • 2
    Polyclonal
    Conjugué
    • 30
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FZD6 est non-conjugé
    Application
    • 27
    • 17
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human FZD6
    Isotype
    IgG
    Top Product
    Discover our top product FZD6 Anticorps primaire
  • Indications d'application
    IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Conseil sur la manipulation
    Avoid freeze / thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Autre désignation
    FZD6 (FZD6 Produits)
    Synonymes
    anticorps zgc:65879, anticorps zgc:77440, anticorps fz6, anticorps frz6, anticorps Xfrz6, anticorps frizzled6, anticorps frizzled-6, anticorps FZ-6, anticorps FZ6, anticorps HFZ6, anticorps NDNC10, anticorps Frizzled-6, anticorps Fz6, anticorps frizzled class receptor 6, anticorps frizzled class receptor 6 S homeolog, anticorps fzd6, anticorps fzd6.S, anticorps FZD6, anticorps Fzd6
    Sujet
    This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
    NCBI Accession
    NP_001158087
    Pathways
    Signalisation WNT, Tube Formation
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