GRK4 anticorps

N° du produit ABIN2428193

Détail du produit anti-GRK4 anticorps

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antigen affinity purification

Immunogène: Recombinant protein of human GRK4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at -20°C (regular) and -80°C (long term).

Détails sur GRK4

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Autre désignation: GRK4 (GRK4 Produits)

Synonymes: anticorps GPRK2L, anticorps GPRK4, anticorps GRK4a, anticorps IT11, anticorps A830025H08Rik, anticorps GRK, anticorps Gprk2l, anticorps Gprk4, anticorps AMPK, anticorps AMPKalpha, anticorps CG3051, anticorps DmAMPK alpha, anticorps Dmel\\CG3051, anticorps EG:132E8.2, anticorps FBgn0023169, anticorps Gprk-4, anticorps ampk, anticorps ampkalpha, anticorps dAMPKa, anticorps dAMPKalpha, anticorps snf1a, anticorps gprk4, anticorps gprk4-a, anticorps grk4, anticorps GRK4, anticorps gprk4-b, anticorps zgc:153020, anticorps gprk2l, anticorps grk4a, anticorps it11, anticorps G protein-coupled receptor kinase 4, anticorps AMP-activated protein kinase alpha subunit, anticorps G protein-coupled receptor kinase 4 L homeolog, anticorps G protein-coupled receptor kinase 4 S homeolog, anticorps GRK4, anticorps Grk4, anticorps AMPKalpha, anticorps grk4.L, anticorps grk4.S, anticorps grk4, anticorps LOC100540688

Sujet: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin, the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
Synonyms: IT11, GPRK4, GRK4a, GPRK2L

Poids moléculaire: Calculated MW: 67 kDa

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling