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HMGCS1 anticorps

HMGCS1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2433131
  • Antigène Voir toutes HMGCS1 Anticorps
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
    Reactivité
    • 41
    • 36
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 60
    • 4
    • 1
    Lapin
    Clonalité
    • 64
    • 1
    Polyclonal
    Conjugué
    • 32
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HMGCS1 est non-conjugé
    Application
    • 43
    • 22
    • 13
    • 13
    • 12
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human HMGCS1
    Isotype
    IgG
    Top Product
    Discover our top product HMGCS1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Conseil sur la manipulation
    Avoid freeze / thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
    Autre désignation
    HMGCS1 (HMGCS1 Produits)
    Synonymes
    anticorps HMGCS, anticorps zgc:56481, anticorps B130032C06Rik, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase 1, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble), anticorps 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, anticorps 3-hydroxy-3-methylglutaryl coenzyme A synthase, anticorps hydroxymethylglutaryl-CoA synthase, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase, anticorps hydroxymethylglutaryl coenzyme A synthase, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog, anticorps HMGCS1, anticorps hmgcs1, anticorps Hmgcs1, anticorps mvaS, anticorps SAS2432, anticorps SZO_RS04705, anticorps SEQ_1109, anticorps NAEGRDRAFT_77778, anticorps hmgcs1.S
    Sujet
    HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
    NCBI Accession
    NP_001091742
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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