RUNX1T1 anticorps

N° du produit ABIN2731254

Détail du produit anti-RUNX1T1 anticorps

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RUNX1T1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Homo sapiens runt-related transcription factor 1, translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human RUNX1T1(NP_783553) produced in HEK293T cell.

Clone: 1H1

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RUNX1T1

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Autre désignation: RUNX1T1 (RUNX1T1 Produits)

Synonymes: anticorps MTG8, anticorps si:ch211-232j17.1, anticorps wu:fi14b07, anticorps zgc:154044, anticorps AML1T1, anticorps CBFA2T1, anticorps CDR, anticorps ETO, anticorps ZMYND2, anticorps Cbfa2t1h, anticorps Cbfa2t1, anticorps runt-related transcription factor 1; translocated to, 1 (cyclin D-related), anticorps RUNX1 translocation partner 1 L homeolog, anticorps RUNX1 translocation partner 1, anticorps runx1t1, anticorps runx1t1.L, anticorps RUNX1T1, anticorps Runx1t1

Sujet: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 63 kDa

ID gène: 862

NCBI Accession: NM_175635

HGNC: 862