RFXAP anticorps

N° du produit ABIN2458011

Détail du produit anti-RFXAP anticorps

Antigène: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFXAP est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFXAP.

Information d'application

Indications d'application: RFXAP antibody can be used for detection of RFXAP by ELISA at 1:62500. RFXAP antibody can be used for detection of RFXAP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFXAP antibody at -20 °C.

Détails sur RFXAP

Antigène: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Autre désignation: RFXAP (RFXAP Produits)

Synonymes: anticorps RFXAP, anticorps 5730495K23Rik, anticorps regulatory factor X associated protein, anticorps regulatory factor X-associated protein, anticorps RFXAP, anticorps rfxap, anticorps Rfxap

Sujet: RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 28 kDa

ID gène: 5994

NCBI Accession: NP_000529

UniProt: O00287