CELF6 anticorps

N° du produit ABIN2458550

Détail du produit anti-CELF6 anticorps

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELF6 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BRUNOL6.

Information d'application

Indications d'application: BRUNOL6 antibody can be used for detection of BRUNOL6 by ELISA at 1:62500. BRUNOL6 antibody can be used for detection of BRUNOL6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BRUNOL6 antibody at -20 °C.

Détails sur CELF6

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Autre désignation: BRUNOL6 (CELF6 Produits)

Synonymes: anticorps BRUNOL6, anticorps 6330569O16Rik, anticorps Brunol6, anticorps CUGBP Elav-like family member 6, anticorps CUGBP, Elav-like family member 6, anticorps CELF6, anticorps Celf6

Sujet: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.

Poids moléculaire: 50 kDa

ID gène: 60677

NCBI Accession: NP_443072

UniProt: Q96J87