CYP46A1 anticorps

N° du produit ABIN2458770

Détail du produit anti-CYP46A1 anticorps

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP46A1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP46A1.

Information d'application

Indications d'application: CYP46A1 antibody can be used for detection of CYP46A1 by ELISA at 1:312500. CYP46A1 antibody can be used for detection of CYP46A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP46A1 antibody at -20 °C.

Détails sur CYP46A1

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Autre désignation: CYP46A1 (CYP46A1 Produits)

Synonymes: anticorps CP46, anticorps CYP46, anticorps CYP46A1, anticorps zgc:109896, anticorps MGC147389, anticorps Cyp46, anticorps cytochrome P450 family 46 subfamily A member 1, anticorps cytochrome P450 family 46 subfamily A member 1 L homeolog, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1, anticorps cytochrome P450, family 46, anticorps cytochrome P450 46A1, anticorps cytochrome P450, family 46, subfamily a, polypeptide 1, anticorps cholesterol 24-hydroxylase, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, anticorps CYP46A1, anticorps cyp46a1.L, anticorps cyp46a1.1, anticorps cyp46a1, anticorps PTRG_08343, anticorps PTRG_09667, anticorps Cyp46a1, anticorps Sgly_1093

Sujet: CYP46A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 57 kDa

ID gène: 10858

NCBI Accession: NP_006659

UniProt: Q9Y6A2