LECT1 anticorps

N° du produit ABIN2458871

Détail du produit anti-LECT1 anticorps

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LECT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LECT1.

Information d'application

Indications d'application: LECT1 antibody can be used for detection of LECT1 by ELISA at 1:1562500. LECT1 antibody can be used for detection of LECT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LECT1 antibody at -20 °C.

Détails sur LECT1

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Autre désignation: LECT1 (LECT1 Produits)

Synonymes: anticorps chm1, anticorps chm-i, anticorps bricd3, anticorps MGC53801, anticorps MGC82444, anticorps chondromodulin-I, anticorps Lect1, anticorps BRICD3, anticorps CHM-I, anticorps CHM1, anticorps MYETS1, anticorps Bricd3, anticorps ChM-I, anticorps Chm-1, anticorps chondromodulin L homeolog, anticorps leukocyte cell derived chemotaxin 1, anticorps chondromodulin, anticorps cnmd.L, anticorps lect1, anticorps CNMD, anticorps cnmd, anticorps Cnmd

Sujet: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 14 kDa

ID gène: 11061

NCBI Accession: NP_008946

UniProt: O75829