WNT6 anticorps

N° du produit ABIN2459042

Détail du produit anti-WNT6 anticorps

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT6 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WNT6.

Information d'application

Indications d'application: WNT6 antibody can be used for detection of WNT6 by ELISA at 1:312500. WNT6 antibody can be used for detection of WNT6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WNT6 antibody at -20 °C.

Détails sur WNT6

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Autre désignation: WNT6 (WNT6 Produits)

Synonymes: anticorps WNT6, anticorps si:dkey-31m21.2, anticorps Wnt6, anticorps AA409270, anticorps Wnt-6, anticorps Xwnt-6, anticorps wnt-6, anticorps wnt6-A, anticorps xWnt6, anticorps Wnt family member 6, anticorps wingless-type MMTV integration site family, member 6b, anticorps wingless-type MMTV integration site family, member 6, anticorps Wnt family member 6 S homeolog, anticorps WNT6, anticorps Wnt6, anticorps wnt6b, anticorps wnt6.S

Sujet: The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.

Poids moléculaire: 37 kDa

ID gène: 7475

NCBI Accession: NP_006513

UniProt: Q9Y6F9

Pathways: Signalisation WNT, Tube Formation