SPOP-B anticorps
-
- Antigène Voir toutes SPOP-B Anticorps
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SPOP-B est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPOP.
- Top Product
- Discover our top product SPOP-B Anticorps primaire
-
-
- Indications d'application
- SPOP antibody can be used for detection of SPOP by ELISA at 1:1562500. SPOP antibody can be used for detection of SPOP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPOP antibody at -20 °C.
-
- Antigène
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Autre désignation
- SPOP (SPOP-B Produits)
- Synonymes
- anticorps BTBD32, anticorps TEF2, anticorps AI315626, anticorps Pcif1, anticorps zgc:64140, anticorps spop, anticorps tef2, anticorps speckle type BTB/POZ protein, anticorps speckle-type POZ protein, anticorps speckle type POZ protein S homeolog, anticorps SPOP, anticorps Spop, anticorps spop, anticorps spop.S
- Sujet
- SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
- Poids moléculaire
- 42 kDa
- ID gène
- 8405
- NCBI Accession
- NP_001007227
- UniProt
- O43791
-