SPO11 anticorps

N° du produit ABIN2459829

Détail du produit anti-SPO11 anticorps

Antigène: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPO11 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPO11.

Information d'application

Indications d'application: SPO11 antibody can be used for detection of SPO11 by ELISA at 1:1562500. SPO11 antibody can be used for detection of SPO11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPO11 antibody at -20 °C.

Détails sur SPO11

Antigène: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Autre désignation: SPO11 (SPO11 Produits)

Synonymes: anticorps CT35, anticorps SPATA43, anticorps TOPVIA, anticorps zgc:77876, anticorps AI449549, anticorps Meiotic recombination protein spo-11, anticorps SPO11, initiator of meiotic double stranded breaks, anticorps SPO11 meiotic protein covalently bound to DSB, anticorps spo-11, anticorps SPO11, anticorps Spo11, anticorps spo11

Sujet: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.

Poids moléculaire: 44 kDa

ID gène: 23626

NCBI Accession: NP_036576

UniProt: Q9Y5K1