NFX1 anticorps
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- Antigène Voir toutes NFX1 Anticorps
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFX1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFX1.
- Top Product
- Discover our top product NFX1 Anticorps primaire
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- Indications d'application
- NFX1 antibody can be used for detection of NFX1 by ELISA at 1:312500. NFX1 antibody can be used for detection of NFX1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFX1 antibody at -20 °C.
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- Antigène
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
- Autre désignation
- NFX1 (NFX1 Produits)
- Synonymes
- anticorps NFX1, anticorps NFX2, anticorps 1300017N15Rik, anticorps 3000003M19Rik, anticorps NFX.1, anticorps TEG-42, anticorps Tex42, anticorps nuclear transcription factor, X-box binding 1, anticorps nuclear transcription factor, x-box binding 1, anticorps NFX1, anticorps CpipJ_CPIJ011986, anticorps nfx1, anticorps Nfx1
- Sujet
- MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
- Poids moléculaire
- 124 kDa
- ID gène
- 4799
- NCBI Accession
- NP_002495
- UniProt
- Q12986
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