T-Box 1 anticorps

N° du produit ABIN2460712

Détail du produit anti-T-Box 1 anticorps

Antigène: T-Box 1 (TBX1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX1.

Information d'application

Indications d'application: TBX1 antibody can be used for detection of TBX1 by ELISA at 1:62500. TBX1 antibody can be used for detection of TBX1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX1 antibody at -20 °C.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: TBX1 (TBX1 Produits)

Synonymes: anticorps CAFS, anticorps CTHM, anticorps DGCR, anticorps DGS, anticorps DORV, anticorps TBX1C, anticorps TGA, anticorps VCFS, anticorps mp:zf637-3-000616, anticorps zgc:136724, anticorps TBX1, anticorps dgs, anticorps tga, anticorps cafs, anticorps cthm, anticorps dgcr, anticorps dorv, anticorps vcfs, anticorps tbx1c, anticorps xtbx1, anticorps tbx1, anticorps T-box 1, anticorps T-box 1 S homeolog, anticorps T-box 1 L homeolog, anticorps TBX1, anticorps Tbx1, anticorps tbx1, anticorps tbx1.S, anticorps tbx1.L

Sujet: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 53 kDa

ID gène: 6899

NCBI Accession: NP_542378

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation