RUNX1T1 anticorps

N° du produit ABIN2460848

Détail du produit anti-RUNX1T1 anticorps

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX1T1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUNX1T1.

Information d'application

Indications d'application: RUNX1T1 antibody can be used for detection of RUNX1T1 by ELISA at 1:312500. RUNX1T1 antibody can be used for detection of RUNX1T1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RUNX1T1 antibody at -20 °C.

Détails sur RUNX1T1

Antigène: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Autre désignation: RUNX1T1 (RUNX1T1 Produits)

Synonymes: anticorps MTG8, anticorps si:ch211-232j17.1, anticorps wu:fi14b07, anticorps zgc:154044, anticorps AML1T1, anticorps CBFA2T1, anticorps CDR, anticorps ETO, anticorps ZMYND2, anticorps Cbfa2t1h, anticorps Cbfa2t1, anticorps runt-related transcription factor 1; translocated to, 1 (cyclin D-related), anticorps RUNX1 translocation partner 1 L homeolog, anticorps RUNX1 translocation partner 1, anticorps runx1t1, anticorps runx1t1.L, anticorps RUNX1T1, anticorps Runx1t1

Sujet: RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t (8,21) (q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.

Poids moléculaire: 62 kDa

ID gène: 862

NCBI Accession: NP_783554

UniProt: Q06455