MBNL2 anticorps

N° du produit ABIN2463438

Détail du produit anti-MBNL2 anticorps

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MBNL2.

Information d'application

Indications d'application: MBNL2 antibody can be used for detection of MBNL2 by ELISA at 1:1562500. MBNL2 antibody can be used for detection of MBNL2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MBNL2 antibody at -20 °C.

Détails sur MBNL2

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Autre désignation: MBNL2 (MBNL2 Produits)

Synonymes: anticorps 1110002M11Rik, anticorps AI047808, anticorps AI837313, anticorps AI849185, anticorps AL118326, anticorps MBLL, anticorps R75232, anticorps mKIAA4072, anticorps wu:fj89c04, anticorps MBLL39, anticorps PRO2032, anticorps muscleblind like splicing factor 2, anticorps muscleblind-like splicing regulator 2, anticorps muscleblind like splicing regulator 2, anticorps Mbnl2, anticorps mbnl2, anticorps MBNL2

Sujet: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

Poids moléculaire: 28 kDa

ID gène: 10150

NCBI Accession: NP_005748

UniProt: O95205