PTPN13 anticorps (AA 212-399)

N° du produit ABIN2468004

Détail du produit anti-PTPN13 anticorps

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Épitope: AA 212-399

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN13 est non-conjugé

Application: Western Blotting (WB)

Purification: Immunoaffinity Purified

Information d'application

Indications d'application: Protein-tyrosine phosphatase antibody can be used for the detection of Protein-tyrosine phosphatase by Western Blot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Agent conservateur: Without preservative

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: PTPN13 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Détails sur PTPN13

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Autre désignation: PTPN13 (PTPN13 Produits)

Synonymes: anticorps FAP-1, anticorps PNP1, anticorps PTP-BAS, anticorps PTP-BL, anticorps PTP1E, anticorps PTPL1, anticorps PTPLE, anticorps hPTP1E, anticorps PTPN13, anticorps AI324989, anticorps Ptpri, anticorps RIP, anticorps Ptp-bl, anticorps ptp, anticorps wu:fb50g04, anticorps zgc:162319, anticorps protein tyrosine phosphatase, non-receptor type 13, anticorps tyrosine-protein phosphatase non-receptor type 13, anticorps PTPN13, anticorps LOC100540743, anticorps ptpn13, anticorps Ptpn13

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Poids moléculaire: 14.2 kDa (calculated)

ID gène: 5783

NCBI Accession: NP_006255

UniProt: Q12923