LMAN1 anticorps (AA 270-470)

N° du produit ABIN2468020

Détail du produit anti-LMAN1 anticorps

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Épitope: AA 270-470

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp LMAN1 est non-conjugé

Application: Western Blotting (WB)

Purification: Immunoaffinity Purified

Information d'application

Indications d'application: ERGIC-53 protein antibody can be used for the detection of ERGIC-53 protein by Western Blot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Agent conservateur: Without preservative

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: LMAN1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Détails sur LMAN1

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Autre désignation: LMAN1 (LMAN1 Produits)

Synonymes: anticorps ERGIC-53, anticorps ERGIC53, anticorps F5F8D, anticorps FMFD1, anticorps MCFD1, anticorps MR60, anticorps gp58, anticorps 2610020P13Rik, anticorps AI326273, anticorps AU043785, anticorps C730041J05, anticorps P58, anticorps p58, anticorps LMAN1, anticorps cpx-iii, anticorps cpxiii, anticorps lman1, anticorps wu:fc54c09, anticorps wu:fi36e01, anticorps Xp58, anticorps lman1-a, anticorps lectin, mannose binding 1, anticorps lectin, mannose-binding, 1, anticorps complexin 3, anticorps lectin, mannose binding 1 S homeolog, anticorps LMAN1, anticorps Lman1, anticorps cplx3, anticorps lman1, anticorps lman1.S

Sujet: FUNCTION: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.

DISEASE: Defects in LMAN1 are a cause of factor V and factor VIII combined deficiency (F5F8D) [MIM:227300], also known as multiple coagulation factor deficiency I (MCFD1). F5F8D is an autosomal recessive bleeding disorder characterized by coordinate reduction of both clotting proteins. Affected patients present with a moderate bleeding tendency and have factor V and factor VIII levels in the range of 5-30 % of normal.

Poids moléculaire: 57.5 kDa (calculated)

ID gène: 3998

NCBI Accession: NP_005561

UniProt: P49257