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GLI2 anticorps (Internal Region)

GLI2 Reactivité: Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2470359
  • Antigène Voir toutes GLI2 Anticorps
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Épitope
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 41
    • 12
    • 4
    • 1
    • 1
    Souris
    Hôte
    • 40
    • 2
    • 1
    Lapin
    Clonalité
    • 41
    • 2
    Polyclonal
    Conjugué
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp GLI2 est non-conjugé
    Application
    • 16
    • 10
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunoaffinity Chromatography
    Immunogène
    GLI2 antibody was raised against amino acids from an internal region of GLI2 (Mouse).
    Top Product
    Discover our top product GLI2 Anticorps primaire
  • Indications d'application
    GLI2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    As with all antibodies avoid freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store GLI2 antibody at 4 °C or -20 °C.
  • Antigène
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Autre désignation
    GLI2 (GLI2 Produits)
    Synonymes
    anticorps HPE9, anticorps THP1, anticorps THP2, anticorps GLI2/GLI4, anticorps GLI3, anticorps AW546128, anticorps GLI family zinc finger 2, anticorps GLI-Kruppel family member GLI2, anticorps GLI2, anticorps Gli2
    Sujet
    Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling, and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes: Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, pre-axial polydactyly type IV, post-axial polydactyly types A1 and B. Expression has been reported for this mRNA in human testis, myometrium, kidney, lung, glioblastomas, and embryonal cell carcinomas. Multiple splice variants have been reported for this protein.
    ID gène
    2736
    UniProt
    P10070
    Pathways
    Signalisation Hedgehog, Dopaminergic Neurogenesis
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