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SOD3 anticorps (AA 227-236) (PE)

SOD3 Reactivité: Humain WB, ICC, IF Hôte: Lapin Polyclonal PE
N° du produit ABIN2482059
  • Antigène Voir toutes SOD3 Anticorps
    SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))
    Épitope
    • 11
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 227-236
    Reactivité
    • 66
    • 30
    • 15
    • 2
    Humain
    Hôte
    • 65
    • 19
    • 2
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 71
    • 18
    Polyclonal
    Conjugué
    • 44
    • 12
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SOD3 est conjugé à/à la PE
    Application
    • 67
    • 37
    • 35
    • 31
    • 24
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects extracellular SOD ~35 kDa.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Peptide Affinity Purified
    Immunogène
    Peptide corresponding to AA 227-236 of human EC SOD
    Top Product
    Discover our top product SOD3 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2482059 was sufficient for detection of ECSOD in 20 μg of Hela lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))
    Autre désignation
    SOD3 (SOD3 Produits)
    Synonymes
    anticorps EC-SOD, anticorps ECSOD, anticorps SOD3, anticorps AI314465, anticorps LOC780439, anticorps fb05f10, anticorps si:dkey-117m1.6, anticorps sod3, anticorps wu:fb05f10, anticorps ECSODPT, anticorps CuZnSOD, anticorps SODA.4, anticorps superoxide dismutase 3, anticorps superoxide dismutase 3, extracellular, anticorps superoxide dismutase 3, extracellular b, anticorps superoxide dismutase 1, anticorps superoxide dismutase precursor ,putative, anticorps SOD3, anticorps Sod3, anticorps sod3b, anticorps sod3, anticorps Sod1, anticorps Smp_095980
    Sujet
    Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (6). SOD3 can also be distinguished by its heparin-binding capacity (1).
    ID gène
    6649
    UniProt
    P08294
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