Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Nav1.8 anticorps (AA 1724-1956) (PerCP)

SCN10A Reactivité: Rat IHC, WB, IF, ICC, AA Hôte: Souris Monoclonal S134 PerCP
N° du produit ABIN2483067
  • Antigène Voir toutes Nav1.8 (SCN10A) Anticorps
    Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
    Épitope
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1724-1956
    Reactivité
    • 18
    • 16
    • 3
    • 1
    Rat
    Hôte
    • 17
    • 14
    • 1
    • 1
    Souris
    Clonalité
    • 19
    • 14
    Monoclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nav1.8 est conjugé à/à la PerCP
    Application
    • 19
    • 19
    • 15
    • 12
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)
    Specificité
    Detects ~220 kDa. No cross reactivity against other Nav channels.
     Réactivité croisée
    Humain, Singe, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 1724-1956 of rat Nav1.8
    Clone
    S134
    Isotype
    IgG2a
    Top Product
    Discover our top product SCN10A Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2483067 was sufficient for detection of Nav1.8 in 10 μg of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
    Autre désignation
    Nav1.8 (SCN10A Produits)
    Synonymes
    anticorps Nav1.8, anticorps PN3, anticorps SNS, anticorps hPN3, anticorps Na(V)1.8, anticorps sodium channel, voltage-gated, type X, alpha, anticorps sodium voltage-gated channel alpha subunit 10, anticorps Scn10a, anticorps SCN10A
    Sujet
    Nav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.
    ID gène
    29571
    NCBI Accession
    NP_058943
    UniProt
    Q62968
Vous êtes ici:
Support technique