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CACNA1G anticorps (AA 2052-2172) (Atto 488)

CACNA1G Reactivité: Souris WB, IHC, IF, ICC Hôte: Souris Monoclonal S178A-9 Atto 488
N° du produit ABIN2483292
  • Antigène Voir toutes CACNA1G Anticorps
    CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
    Épitope
    • 16
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 2052-2172
    Reactivité
    • 34
    • 25
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 24
    • 13
    • 1
    Souris
    Clonalité
    • 25
    • 13
    Monoclonal
    Conjugué
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CACNA1G est conjugé à/à la Atto 488
    Application
    • 19
    • 18
    • 14
    • 13
    • 13
    • 12
    • 11
    • 7
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~<200 kDa. Does not cross-react with Cav3.2.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1
    Clone
    S178A-9
    Isotype
    IgG1
    Top Product
    Discover our top product CACNA1G Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2483292 was sufficient for detection of Cav3.1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
    Autre désignation
    Cav3.1 (CACNA1G Produits)
    Synonymes
    anticorps CACNA1G, anticorps cav3.1, anticorps ca(v)3.1, anticorps Ca(V)T.1, anticorps Cav3.1, anticorps NBR13, anticorps Cav3.1d, anticorps [a]1G, anticorps a1G, anticorps alpha-1G, anticorps mKIAA1123, anticorps Ca(v)3.1, anticorps calcium voltage-gated channel subunit alpha1 G, anticorps calcium channel, voltage-dependent, T type, alpha 1G subunit, anticorps calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog, anticorps CACNA1G, anticorps cacna1g, anticorps cacna1g.L, anticorps Cacna1g
    Sujet
    Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (1). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic's, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (1). Much remains to be determined about the precise cellular localization, in vivo physiological roles, roles in disease states and possible routes to modulate their structure/function to ameliorate effects of disease.
    ID gène
    12291
    NCBI Accession
    NP_001106284
    UniProt
    Q9WUT2
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