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SLC17A7 anticorps (AA 493-560) (Biotin)

SLC17A7 Reactivité: Rat WB, IHC Hôte: Souris Monoclonal S28-9 Biotin
N° du produit ABIN2483726
  • Antigène Voir toutes SLC17A7 Anticorps
    SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
    Épitope
    • 11
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 493-560
    Reactivité
    • 47
    • 35
    • 30
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Rat
    Hôte
    • 32
    • 15
    • 2
    • 2
    • 1
    Souris
    Clonalité
    • 37
    • 15
    Monoclonal
    Conjugué
    • 24
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC17A7 est conjugé à/à la Biotin
    Application
    • 48
    • 24
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Detects ~52 kDa. No cross-reactivity against VGlut2.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
    Clone
    S28-9
    Isotype
    IgG1
    Top Product
    Discover our top product SLC17A7 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2483726 was sufficient for detection of VGLut1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
    Autre désignation
    VGLUT1 (SLC17A7 Produits)
    Synonymes
    anticorps 2900052E22Rik, anticorps AI851913, anticorps VGluT1, anticorps Vglut1, anticorps BNPI, anticorps VGLUT1, anticorps slc17a7, anticorps vglut1, anticorps solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, anticorps solute carrier family 17 member 7, anticorps solute carrier family 17 (vesicular glutamate transporter), member 7a, anticorps Slc17a7, anticorps SLC17A7, anticorps slc17a7a
    Sujet
    VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
    ID gène
    116638
    NCBI Accession
    NP_446311
    UniProt
    Q62634
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