HCN3 anticorps (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3) (AA 660-779) (APC)

Details for Product anti-HCN3 Antibody No. ABIN2483844, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCNG-4
  • Bcng4
  • Hac3
  • Hcn4
  • hyperpolarization activated cyclic nucleotide gated potassium channel 3
  • hyperpolarization-activated cyclic nucleotide-gated potassium channel 3
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 3
  • HCN3
  • Hcn3
Épitope
AA 660-779
54
25
20
10
3
2
2
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
102
97
76
4
4
2
2
2
1
1
1
Hôte
Souris
58
35
29
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp HCN3 est conjugé à/à la APC
6
6
5
5
5
4
3
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Antibody Array (AA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
109
60
40
37
36
18
18
17
13
4
2
2
2
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Fusion protein amino acids 660-779 (C terminus) of mouse HCN3
Clone S141-28
Isotype IgG1
Specificité Detects ~90 kDa. No cross-reactivity against other HCNs.
Purification Protein G Purified
Plasmids, Primers & others Plasmids, Primers & others HCN3 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation HCN3 (HCN3 Antibody Extrait)
Sujet Hyperpolarization-activated cation channels of the HCN gene family contribute to spontaneous rhythmic activity in both the heart and brain (1).
ID gène 15168
NCBI Accession NP_032253
UniProt O88705
Indications d'application
  • WB (1:1000)
  • IHC (1:1000)
  • ICC/IF (1:100)
  • optimal dilutions for assays should be determined by the user.
Commentaires

1 μg/ml of SMC-306 was sufficient for detection of HCN3 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Images (Fournisseur)
Immunohistochemistry (IHC) image for anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3) (AA 660-779) antibody (APC) (ABIN2483844) Immunohistochemistry analysis using Mouse Anti-HCN3 Monoclonal Antibody, Clone S141-2...
Western Blotting (WB) image for anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3) (AA 660-779) antibody (APC) (ABIN2483844) Western Blot analysis of Rat brain membrane lysate showing detection of HCN3 protein ...
Immunohistochemistry (IHC) image for anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3) (AA 660-779) antibody (APC) (ABIN2483844) Immunohistochemistry analysis using Mouse Anti-HCN3 Monoclonal Antibody, Clone S141-2...
Background publications Zong, Eckert, Yuan, Wahl-Schott, Abicht, Fang, Li, Mistrik, Gerstner, Much, Baumann, Michalakis, Zeng, Chen, Biel: "A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase." dans: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34224-32, 2005 (PubMed).

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