ATP7B anticorps (AA 3-21) (FITC)

N° du produit ABIN2485175

Détail du produit anti-ATP7B anticorps (FITC)

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Épitope: AA 3-21

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATP7B est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité: Detects ~160 kDa in rat brain membrane preparations.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2

Clone: S62-29

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2485175 was sufficient for detection of Copper-transporting ATPase2 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur ATP7B

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Autre désignation: ATP7B (ATP7B Produits)

Synonymes: anticorps PWD, anticorps WC1, anticorps WD, anticorps WND, anticorps Atp7a, anticorps tx, anticorps Hts, anticorps PINA, anticorps Wd, anticorps ATP7B, anticorps ATPase copper transporting beta, anticorps ATPase, Cu++ transporting, beta polypeptide, anticorps ATPase, Cu++ transporting, beta polypeptide (Wilson disease), anticorps copper-transporting ATPase 2, anticorps ATP7B, anticorps Atp7b, anticorps atp7b, anticorps LOC592143

Sujet: The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene, A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage.

ID gène: 540

NCBI Accession: NP_000044

UniProt: B7ZLR4

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process