TRPC7 anticorps (AA 845-862) (Biotin)
Aperçu rapide pour TRPC7 anticorps (AA 845-862) (Biotin) (ABIN2485429)
Antigène
Voir toutes TRPC7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 845-862
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Specificité
- Detects ~100 kDa.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Protein G Purified
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Immunogène
- Synthetic peptide amino acids 845-862 of human TRPC7
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Isotype
- IgG1
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Indications d'application
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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1 μg/ml of ABIN2485429 was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))
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Autre désignation
- TRPC7
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Sujet
- Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).
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ID gène
- 57113
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NCBI Accession
- NP_065122
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UniProt
- Q9HCX4
Antigène
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