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Erythrocyte Ankyrin anticorps (AA 1-1881) (Alkaline Phosphatase (AP))

ANK1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S388A-10 Alkaline Phosphatase (AP)
N° du produit ABIN2485530
  • Antigène Voir toutes Erythrocyte Ankyrin (ANK1) Anticorps
    Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
    Épitope
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-1881
    Reactivité
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 13
    • 12
    • 1
    • 1
    Souris
    Clonalité
    • 15
    • 12
    Monoclonal
    Conjugué
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Erythrocyte Ankyrin est conjugé à/à la Alkaline Phosphatase (AP)
    Application
    • 23
    • 16
    • 12
    • 10
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~200 kDa. Does not cross-react with Ankyrin-B or Ankyrin-G.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R
    Clone
    S388A-10
    Isotype
    IgG2b
    Top Product
    Discover our top product ANK1 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:100 dilution of ABIN2485530 was sufficient for detection of Ankyrin R in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
    Autre désignation
    Ankyrin R (ANK1 Produits)
    Synonymes
    anticorps CHANK1, anticorps wu:fa09h06, anticorps zgc:101835, anticorps ank, anticorps sph1, anticorps sph2, anticorps ANK1, anticorps ANK, anticorps SPH1, anticorps SPH2, anticorps Ank-1, anticorps nb, anticorps pale, anticorps ankyrin 1, anticorps ankyrin 1, erythrocytic a, anticorps ankyrin 1 L homeolog, anticorps ankyrin 1, erythrocytic, anticorps ankyrin 1, erythroid, anticorps ANK1, anticorps ank1a, anticorps ank1, anticorps ank1.L, anticorps Ank1
    Sujet
    Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane. Ankyrin R, or Ank1, was first discovered in erythrocyres, but has since also been located in the brain and muscles. Mutations are associated with hereditary spehrocytosis and alzheimer's diease (2).
    ID gène
    286
    NCBI Accession
    NP_000028
    UniProt
    P16157
    Pathways
    Synaptic Membrane
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