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Glutamate Receptor 1 anticorps (AA 1-389) (APC)

GLUR1 Reactivité: Rat WB, IHC, IF, ICC Hôte: Souris Monoclonal S355-1 APC
N° du produit ABIN2485602
  • Antigène Voir toutes Glutamate Receptor 1 (GLUR1) Anticorps
    Glutamate Receptor 1 (GLUR1)
    Épitope
    • 17
    • 17
    • 15
    • 15
    • 13
    • 13
    • 12
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-389
    Reactivité
    • 112
    • 112
    • 94
    • 11
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 124
    • 25
    • 1
    Souris
    Clonalité
    • 113
    • 37
    Monoclonal
    Conjugué
    • 75
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glutamate Receptor 1 est conjugé à/à la APC
    Application
    • 102
    • 40
    • 40
    • 40
    • 37
    • 27
    • 16
    • 15
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~100 kDa. Does not cross-react with GluR2.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1
    Clone
    S355-1
    Isotype
    IgG1
    Top Product
    Discover our top product GLUR1 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2485602 was sufficient for detection of GluA1/GluR1 in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Glutamate Receptor 1 (GLUR1)
    Autre désignation
    GluR1 (GLUR1 Produits)
    Synonymes
    anticorps GLUH1, anticorps GLUR1, anticorps GLURA, anticorps GluA1, anticorps HBGR1, anticorps gluR-A, anticorps 2900051M01Rik, anticorps Glr-1, anticorps Glr1, anticorps GluR-A, anticorps GluRA, anticorps Glur-1, anticorps Glur1, anticorps HIPA1, anticorps gluR-K1, anticorps GRIA1, anticorps glur1, anticorps Gria1, anticorps glur1b, anticorps gria1.2, anticorps sb:eu293, anticorps ZfGluR1a, anticorps glur1a, anticorps gria1.1, anticorps zfGRIA1[a], anticorps glutamate ionotropic receptor AMPA type subunit 1, anticorps glutamate receptor, ionotropic, AMPA1 (alpha 1), anticorps glutamate receptor, ionotropic, AMPA 1, anticorps glutamate receptor, ionotropic, AMPA 1 L homeolog, anticorps GluR1 protein, anticorps Glutamate receptor 1, anticorps glutamate receptor, ionotropic, AMPA 1b, anticorps glutamate receptor, ionotropic, AMPA 1a, anticorps GRIA1, anticorps Gria1, anticorps gria1, anticorps gria1.L, anticorps glur1, anticorps glr-1, anticorps gria1b, anticorps gria1a
    Sujet
    Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
    ID gène
    50592
    NCBI Accession
    NP_113796
    UniProt
    P19490
    Pathways
    Signalisation PI3K-Akt
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