Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2) (AA 911-929) anticorps (PerCP)

N° du produit ABIN2486313

Détail du produit

Antigène: Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)

Épitope: AA 911-929

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: PerCP

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Specificité: Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney. Isoform 3 and isoform 4 are expressed in both the inner and outer renal medulla.,Detects ~97 and 127 kDa.

Réactivité croisée: Souris, Rat

Purification: Peptide Affinity Purified

Immunogène: Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)

Information d'application

Indications d'application:

• WB (1:1000)
• IHC (1:25)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2486313 was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détail du antigène

Antigène: Solute Carrier Family 14 (Urea Transporter, Kidney) Member 2 (SLC14A2)

Autre désignation: UT-A1 (SLC14A2 Produits)

Synonymes: anticorps HUT2, anticorps UT-A2, anticorps UT2, anticorps UTA, anticorps UTR, anticorps hUT-A6, anticorps Slc14a2T, anticorps Slc14a2_v4, anticorps UrT1-C, anticorps UrT1-D, anticorps testSymbol, anticorps UT-A1, anticorps UT-A3, anticorps solute carrier family 14 member 2, anticorps solute carrier family 14 (urea transporter), member 2, anticorps SLC14A2, anticorps Slc14a2

Sujet: UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2) (1, 2).

ID gène: 54302

NCBI Accession: NP_062220

UniProt: Q62668

Pathways: Response to Water Deprivation