BBC3 anticorps (BCL2 Binding Component 3)

Details for Product anti-BBC3 Antibody No. ABIN252347
Antigène
  • BBC3
  • Puma
  • JFY-1
  • JFY1
  • PUMA
  • PUMA/JFY1
  • BCL2 binding component 3
  • Bcl-2 binding component 3
  • BBC3
  • Bbc3
  • bbc3
Reactivité
Humain, Souris
265
124
108
24
6
1
Hôte
Lapin
235
29
7
Clonalité
Polyclonal
Conjugué
Cet anticorp BBC3 est non-conjugé
10
9
8
7
7
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
234
80
68
39
34
23
22
13
13
6
3
2
2
1
1
Options
Immunogène A portion of amino acids 186-199 (PLPRGHRAPEMEPN ) of human PUMA a was used as the immunogen.
Specificité The amino acid sequence used as immunogen is 100 % homologous in human (PUMA a and b) and 78 % homologous in mouse and rat. Human PUMA a is a 193 amino acid protein with a predicted molecular weight of approximately 22 kD. Human PUMA b is a 131 amino acid protein with a predicted molecular weight of approximately 15 kD.
Purification Protein G purified
Plasmids, Primers & others Plasmids, Primers & others BBC3 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PUMA (BBC3 Antibody Extrait)
Sujet Gene Symbol: BBC3
ID gène 27113
Pathways Signalisation p53, Positive Regulation of Endopeptidase Activity
Indications d'application Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:250, Immunohistochemistry-Paraffin 1:50-1:250Immunohistochemistry-Paraffin: See Karst et al, 2005
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % gelatin
Buffer contains: 0.05 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock 4 °C,-20 °C
Stockage commentaire Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Images (Fournisseur)
Image no. 1 for anti-BCL2 Binding Component 3 (BBC3) antibody (ABIN252347) Western blot analysis for Puma a(CT) using ABIN252347 at 1:500 against 30 ug/lane of ...
Image no. 2 for anti-BCL2 Binding Component 3 (BBC3) antibody (ABIN252347) PUMA expression in human dysplastic nevi (premalignant melanoma).
Image no. 3 for anti-BCL2 Binding Component 3 (BBC3) antibody (ABIN252347) Immunohistochemistry-Paraffin: PUMA Antibody [ABIN2523470] - IHC analysis of a formal...
Image no. 4 for anti-BCL2 Binding Component 3 (BBC3) antibody (ABIN252347) Immunohistochemistry-Paraffin: PUMA Antibody [ABIN2523470] - IHC analysis of a formal...
Produit citée dans: Liao, Chu, Hu, Merkin, Chen, Liu, Degenhardt, White, Ryazanov: "Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival." dans: The Journal of biological chemistry, Vol. 291, Issue 37, pp. 19545-57, 2016 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Kim, Jung, Lee, Lee, Kang, Lee, Park, Han, Lee, Ramkumar, Sung, Kim: "SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53." dans: American journal of physiology. Renal physiology, Vol. 301, Issue 2, pp. F427-35, 2011 (PubMed).

Speidel, Helmbold, Deppert: "Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress." dans: Oncogene, Vol. 25, Issue 6, pp. 940-53, 2006 (PubMed). Détails: Western Blotting

Karst, Dai, Martinka, Li: "PUMA expression is significantly reduced in human cutaneous melanomas." dans: Oncogene, Vol. 24, Issue 6, pp. 1111-6, 2005 (PubMed). Détails: Immunohistochemistry (Paraffin-embedded Sections)

Hershko, Ginsberg: "Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis." dans: The Journal of biological chemistry, Vol. 279, Issue 10, pp. 8627-34, 2004 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

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