FBXO32 anticorps

N° du produit ABIN2562558

Détail du produit anti-FBXO32 anticorps

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO32 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human FBXO32

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:1000

Commentaires:

Specifically expressed in cardiac and skeletal muscle

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur FBXO32

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Autre désignation: FBXO32 (FBXO32 Produits)

Synonymes: anticorps MGC56479, anticorps zgc:56479, anticorps Fbx32, anticorps MAFbx, anticorps 4833442G10Rik, anticorps AI430017, anticorps ATROGIN1, anticorps Gm20361, anticorps Atrogin1, anticorps F-box protein 32, anticorps fbxo32, anticorps FBXO32, anticorps Fbxo32

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 41.637 kDa

ID gène: 114907

UniProt: Q969P5