CYP3A5 anticorps (C-Term)

N° du produit ABIN264500

Détail du produit anti-CYP3A5 anticorps

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Épitope: C-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CYP3A5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody reacts to Cytochrome P450 3A5.

Attributs du produit: Synonyms: Cytochrome P450 3A5, Cytochrome P450-PCN3, Cytochrome P450 HLp2

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human CYP3A5 protein and mousemyeloma Ag8563 cells.

Clone: F18 P3 B6

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. When used in conjunction with CYP3A7 (Cat. No. ABIN264501), can differentiate betweenthe CYP3A family members, 3A5 and 3A7. Positive Control: Squamous oesophagus cancer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CYP3A5

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Autre désignation: CYP3A5 (CYP3A5 Produits)

Synonymes: anticorps CP35, anticorps CYPIIIA5, anticorps P450PCN3, anticorps PCN3, anticorps cytochrome P450 family 3 subfamily A member 5, anticorps CYP3A5

Sujet: CYP3A genes encode monooxygenases, enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A (cytochrome P450, family 3, subfamily A), the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50 % of all clinical drugs. CYP3A members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster consists of four genes: CYP3A43, CYP3A4, CYP3A7 and CYP3A5, and two pseudogenes: CYP3A5P1 and CYP3A5P2. The CYP3A cluster maps to gene locus 7q21.3-q22.1.Synonyms: Cytochrome P450 3A5, Cytochrome P450 HLp2, Cytochrome P450-PCN3

ID gène: 1577

UniProt: P20815

Pathways: Steroid Hormone Biosynthesis