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BNIP3L/NIX anticorps (AA 77-92)

BNIP3L Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN264993
  • Antigène Voir toutes BNIP3L/NIX (BNIP3L) Anticorps
    BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
    Épitope
    • 15
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 77-92
    Reactivité
    • 56
    • 34
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 67
    • 3
    • 1
    Lapin
    Clonalité
    • 66
    • 5
    Polyclonal
    Conjugué
    • 36
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BNIP3L/NIX est non-conjugé
    Application
    • 34
    • 32
    • 27
    • 17
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Specificité
    This antibody recognizes Bnip3L (IN) (nix).
    Purification
    Purified
    Immunogène
    Synthetic peptide corresponding to amino acids 77 to 92 of the human Bnip3L protein. Immunogen sequence is identical in the mouse protein.
    Isotype
    IgG
    Top Product
    Discover our top product BNIP3L Anticorps primaire
  • Indications d'application
    Western Blot: 0.5 to 1 μg/mL. Detects a 40 kDa band in K562 cell lysate which representsthe monomer of Bnip3L.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide as a preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE!
    Stock
    4 °C
    Stockage commentaire
    The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
  • Zhang, Randall, Loyd, Dorsey, Kundu, Cleveland, Ney: "Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation." dans: Blood, Vol. 114, Issue 1, pp. 157-64, (2009) (PubMed).

    Qiu, Jiang, Xiang: "A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3392-403, (2008) (PubMed).

    Marusyk, Wheeler, Mathews, DeGregori: "p53 mediates senescence-like arrest induced by chronic replicational stress." dans: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5336-51, (2007) (PubMed).

    Aerbajinai, Giattina, Lee, Raffeld, Miller: "The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation." dans: Blood, Vol. 102, Issue 2, pp. 712-7, (2003) (PubMed).

    Clase, Lyman, del Rio, Randall, Calton, Enquist, Banfield: "The pseudorabies virus Us2 protein, a virion tegument component, is prenylated in infected cells." dans: Journal of virology, Vol. 77, Issue 22, pp. 12285-98, (2003) (PubMed).

  • Antigène
    BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
    Autre désignation
    BNIP3L / BNIP3A (BNIP3L Produits)
    Synonymes
    anticorps BNIP3a, anticorps NIX, anticorps NIP3, anticorps Nix, anticorps Nip3, anticorps C86132, anticorps D14Ertd719e, anticorps Nip3L, anticorps bnip3l, anticorps nip3, anticorps zgc:110478, anticorps bnip3l2, anticorps wu:fb52b03, anticorps wu:fc02h04, anticorps BCL2 interacting protein 3 like, anticorps BCL2 interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3-like, anticorps BCL2/adenovirus E1B interacting protein 3-like b, anticorps BCL2/adenovirus E1B interacting protein 3-like a, anticorps BNIP3L, anticorps BNIP3, anticorps Bnip3l, anticorps Bnip3, anticorps bnip3lb, anticorps bnip3la
    Sujet
    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X) (1-3). Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis (2,3). Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues (1,2). Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.Synonyms: Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, BNIP3H, NIP3-like protein X, NIX
    ID gène
    665
    NCBI Accession
    NP_004322
    UniProt
    O60238
    Pathways
    Autophagy
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