CACNA1I anticorps

N° du produit ABIN265034

Détail du produit anti-CACNA1I anticorps

Antigène: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1I est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to CACNA1I.

Purification: Purified

Immunogène: Synthetic peptide derived from the rat alpha1I calcium channel conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur CACNA1I

Antigène: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Autre désignation: CACNA1I (CACNA1I Produits)

Synonymes: anticorps CACNA1L, anticorps Ca(V)3.3, anticorps Cav3.3, anticorps ca(v)3.3, anticorps si:ch211-51h13.1, anticorps Ca(v)3.3, anticorps calcium voltage-gated channel subunit alpha1 I, anticorps voltage-dependent T-type calcium channel subunit alpha-1I, anticorps calcium channel, voltage-dependent, alpha 1I subunit, anticorps calcium channel, voltage-dependent, T type, alpha 1I subunit, anticorps CACNA1I, anticorps LOC100555412, anticorps Cacna1i, anticorps cacna1i

Sujet: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Using co-transfection techniques we investigated the functional effects of each of the gamma subunits on the biophysics of the T-type VSCC encoded by the alpha(1I) subunit. This revealed a substantially slowed rate of deactivation in the presence of gamma(2). In contrast, there was no significant corresponding effect of either gamma(3) or gamma(4) on alpha(1I) subunit-mediated currents.(2)Synonyms: Ca(v)3.3, Cav3.3, KIAA1120, Voltage-dependent T-type calcium channel subunit alpha-1I, Voltage-gated calcium channel subunit alpha Cav3.3

ID gène: 8911

NCBI Accession: NP_001003406

UniProt: Q9P0X4