SLA anticorps

N° du produit ABIN265047

Détail du produit anti-SLA anticorps

Antigène: SLA (Src-Like-Adaptor (SLA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLA est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to SLA.

Purification: Purified

Immunogène: Synthetic peptide derived from the human SLAP1 protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur SLA

Antigène: SLA (Src-Like-Adaptor (SLA))

Autre désignation: SLA (SLA Produits)

Synonymes: anticorps SLA1, anticorps SLAP, anticorps src-like-adapter, anticorps SLA, anticorps Slap1, anticorps Slap, anticorps Slap-1, anticorps Src like adaptor, anticorps Src-like-adaptor, anticorps src-like adaptor, anticorps SLA, anticorps Sla

Sujet: Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Interacts with EPHA2, VAV1, LCP2 and PDGFRB. The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.Synonyms: SLAP, SLAP-1, SLAP1, Src-like-adapter, Src-like-adapter protein 1

ID gène: 6503

NCBI Accession: NP_001039021

UniProt: Q13239