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MAPKBP1 anticorps

MAPKBP1 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2650930
  • Antigène Voir toutes MAPKBP1 Anticorps
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    Reactivité
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 7
    • 1
    Lapin
    Clonalité
    • 8
    Polyclonal
    Conjugué
    • 8
    Cet anticorp MAPKBP1 est non-conjugé
    Application
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human MAPKBP1
    Isotype
    IgG
    Top Product
    Discover our top product MAPKBP1 Anticorps primaire
  • Indications d'application
    WB 1:200 - 1:500
    IHC 1:50 - 1:100
    Commentaires

    Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    Autre désignation
    MAPKBP1 (MAPKBP1 Produits)
    Synonymes
    anticorps MGC83682, anticorps JNKBP-1, anticorps 2810483F24Rik, anticorps AW123212, anticorps Jnkbp1, anticorps mKIAA0596, anticorps mitogen-activated protein kinase binding protein 1 L homeolog, anticorps mitogen-activated protein kinase binding protein 1, anticorps mitogen activated protein kinase binding protein 1, anticorps mapkbp1.L, anticorps MAPKBP1, anticorps Mapkbp1
    Sujet
    This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
    Poids moléculaire
    163.818 kDa
    ID gène
    23005
    UniProt
    O60336
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