LASS1 anticorps

N° du produit ABIN265221

Détail du produit anti-LASS1 anticorps

Antigène: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LASS1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Lass1. Detects also GDF1.

Réactivité croisée (Details): Cross reacts with GDF1

Purification: Purified

Immunogène: Synthetic peptide derived from the human Lass1 protein

Isotype: IgG

Information d'application

Indications d'application: Western Blot (1-5 μg/mL). Positive control: Hypothalamus.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur LASS1

Antigène: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Autre désignation: LASS1 (CERS1 Produits)

Synonymes: anticorps LAG1, anticorps LASS1, anticorps UOG1, anticorps Lass1, anticorps Uog-1, anticorps to, anticorps LAG1 HOMOLOG 1, anticorps LONGEVITY ASSURANCE GENE 1, anticorps ceramide synthase 1, anticorps TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein, anticorps CERS1, anticorps Cers1, anticorps LAG1

Sujet: LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane, LAss1 is a multi-pass membrane protein.Synonyms: LAG1, LAG1 longevity assurance homolog 1, LASS1, Longevity assurance gene 1 protein homolog 1, UOG1

ID gène: 10715

NCBI Accession: NP_067090

UniProt: P27544