The antibody was purified by affinity chromatography.
0.22 μm filtered
Optimal working dilution should be determined by the investigator.
For Research Use only
0.22 μm filtered protein solution is in PBS, pH 7.2.
Conseil sur la manipulation
Avoid freeze/thaw cycles.
Aliquot and store at -20°C.
(RNA Polymerase II 33kD Subunit (RPII33))
RNA Polymerase II RPB3
Classe de substances
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The RNA polymermase II subunit RPB3 is a component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft and is known to be involved in transcription termination.