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Interleukin 17a anticorps (FITC)

IL17A Reactivité: Souris ICFC Hôte: Rat Monoclonal TC11-18H10-1 FITC
N° du produit ABIN2661940
  • Antigène Voir toutes Interleukin 17a (IL17A) Anticorps
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Reactivité
    • 103
    • 54
    • 19
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Souris
    Hôte
    • 62
    • 52
    • 29
    • 8
    • 3
    Rat
    Clonalité
    • 81
    • 72
    • 1
    Monoclonal
    Conjugué
    • 69
    • 24
    • 15
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Interleukin 17a est conjugé à/à la FITC
    Application
    • 74
    • 64
    • 49
    • 15
    • 12
    • 12
    • 12
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    TC11-18H10-1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL17A Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Autre désignation
    IL-17A (IL17A Produits)
    Synonymes
    anticorps CTLA8, anticorps IL-17, anticorps IL-17A, anticorps IL17, anticorps Ctla-8, anticorps Ctla8, anticorps Il17, anticorps ChIL-17, anticorps IL-17F, anticorps IL17A, anticorps CTLA-8, anticorps interleukin 17A, anticorps IL17A, anticorps Il17a
    Sujet
    IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
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