PARP1 anticorps (N-Term)

N° du produit ABIN2668274

Détail du produit anti-PARP1 anticorps

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Purification: None

Immunogène: This PARP-1 N-terminal antibody was raised against a His-tagged fusion protein corresponding to the N-terminal half of human PARP-1 was used to generate this PARP-1 antibody.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-PARP1 (ABIN2668274)

Myers, Peddada, Chatterjee, Friedrich, Tomoda, Krings, Thomas, Maynard, Broeker, Thomson, Pollard, Yamanaka, Burlingame, Panning: "SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells." dans: eLife, Vol. 5, pp. e10647, (2016) (PubMed).

Watanabe, Papoutsoglou, Maturi, Tsubakihara, Hottiger, Heldin, Moustakas: "Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation." dans: The Journal of biological chemistry, Vol. 291, Issue 24, pp. 12706-23, (2016) (PubMed).

Matveeva, Maiorano, Zhang, Eteleeb, Convertini, Chen, Infantino, Stamm, Wang, Rouchka, Fondufe-Mittendorf: "Involvement of PARP1 in the regulation of alternative splicing." dans: Cell discovery, Vol. 2, pp. 15046, (2016) (PubMed).

Krishnakumar, Gamble, Frizzell, Berrocal, Kininis, Kraus: "Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes." dans: Science (New York, N.Y.), Vol. 319, Issue 5864, pp. 819-21, (2008) (PubMed).

Kim, Mauro, Gévry, Lis, Kraus: "NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1." dans: Cell, Vol. 119, Issue 6, pp. 803-14, (2004) (PubMed).

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP-1 (PARP1 Produits)

Synonymes: anticorps ADPRT, anticorps ADPRT 1, anticorps ADPRT1, anticorps ARTD1, anticorps PARP, anticorps PARP-1, anticorps PPOL, anticorps pADPRT-1, anticorps Adprt, anticorps Parp-1, anticorps 5830444G22Rik, anticorps AI893648, anticorps Adprp, anticorps Adprt1, anticorps C80510, anticorps parp-1, anticorps sPARP-1, anticorps BEST:LD21673, anticorps CG17685, anticorps CG17696, anticorps CG17718, anticorps CG40411, anticorps D.PARP, anticorps Dm.pARTa, anticorps Dmel\\CG40411, anticorps LD21673.3prime, anticorps PARP1, anticorps dPARP, anticorps parp, anticorps adprt1, anticorps padprt-1, anticorps ppol, anticorps si:dkey-206f10.3, anticorps wu:fc60f12, anticorps zgc:110092, anticorps poly(ADP-ribose) polymerase 1, anticorps poly (ADP-ribose) polymerase 1, anticorps poly (ADP-ribose) polymerase family, member 1, anticorps Poly-(ADP-ribose) polymerase, anticorps poly(ADP-ribose) polymerase 1 L homeolog, anticorps PARP1, anticorps Parp1, anticorps Parp, anticorps parp1.L, anticorps parp1

Poids moléculaire: 120 kDa

ID gène: 142

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location