MLL/KMT2A anticorps (AA 161-356)

N° du produit ABIN2668648

Détail du produit anti-MLL/KMT2A anticorps

Antigène: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Épitope: AA 161-356

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLL/KMT2A est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)

Purification: Protein G Chromatography

Immunogène: This MLL1 antibody was raised against a recombinant protein corresponding to amino acids 161-356 of mouse MLL1.

Clone: N4-4

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-MLL/KMT2A (ABIN2668648)

Aguilar-Arnal, Katada, Orozco-Solis, Sassone-Corsi: "NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1." dans: Nature structural & molecular biology, Vol. 22, Issue 4, pp. 312-8, (2015) (PubMed).

Jin, Zhao, Yi, Nakata, Kalota, Gewirtz: "c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis." dans: The Journal of clinical investigation, Vol. 120, Issue 2, pp. 593-606, (2010) (PubMed).

Détails sur MLL/KMT2A

Antigène: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Autre désignation: MLL / HRX (MLL Produits)

Poids moléculaire: 440 kDa

ID gène: 4297

Pathways: L'effet Warburg