JNK anticorps (Mitogen-Activated Protein Kinase 8)

Details for Product anti-MAPK8 Antibody No. ABIN2687986
Antigène
  • JNK
  • JNK-46
  • JNK1
  • JNK1A2
  • JNK21B1/2
  • PRKM8
  • SAPK1
  • SAPK1c
  • AI849689
  • Prkm8
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • T10F20.15
  • jnk1
  • sapk1
  • mapk8
  • zgc:112379
  • JNKb
  • mapk8b
  • mitogen-activated protein kinase 8
  • Stress-activated protein kinase jnk-1
  • basket
  • Protein kinase superfamily protein
  • mitogen-activated protein kinase 8 L homeolog
  • mitogen-activated protein kinase 8b
  • mitogen-activated protein kinase 8B-like
  • MAPK8
  • jnk-1
  • Mapk8
  • bsk
  • ATMPK8
  • mapk8.L
  • mapk8b
  • LOC109094263
Reactivité
Humain, Souris, Rat (Rattus)
439
203
182
24
19
15
11
9
8
4
3
2
2
2
2
1
1
1
1
Hôte
Lapin
358
91
3
2
Clonalité
Polyclonal
Conjugué
Cet anticorp JNK est non-conjugé
22
16
15
11
11
10
7
7
7
7
7
7
3
3
3
3
3
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
337
208
125
80
71
58
39
37
21
19
18
11
4
4
3
3
2
1
1
1
1
1
Options
Immunogène Synthetic peptide conjugated to KLH
Isotype IgG
Specificité Not yet tested in other species.
Purification Affinity purified
Plasmids, Primers & others Plasmids, Primers & others JNK products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation JNK1 (MAPK8 Antibody Extrait)
Sujet This gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Pathways Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
Indications d'application Peptide ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:200-1000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use.
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer PBS, pH 7.4 with 0.02 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
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