Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) anticorps (Biotin)

Détails pour le produit réf. ABIN2689107
Antigène
  • BLAST-2
  • CD23
  • CD23A
  • CLEC4J
  • FCE2
  • IGEBF
  • Fcer2a
  • Fc fragment of IgE receptor II
  • FCER2
  • Fcer2
Reactivité
Humain
258
125
41
1
Hôte
Souris
185
89
68
Clonalité (Clone)
Monoclonal ()
Conjugué
Biotin
46
34
17
13
4
3
3
3
3
3
3
3
3
2
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA
197
92
87
54
52
43
23
13
12
3
2
2
1
1
Options
Marque BD Pharmingen™
Clone M
Isotype IgG1, kappa
Attributs du produit The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD23 - Biotin - Clone M-L233 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Antigène
Autre désignation CD23 (FCER2 Antibody Extrait)
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Stock 4 °C
Stockage commentaire Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Produit citée dans: Rieber, Rank, Köhler, Krauss: "Membrane expression of Fc epsilon RII/CD23 and release of soluble CD23 by follicular dendritic cells." dans: Advances in experimental medicine and biology, Vol. 329, pp. 393-8, 1993 (PubMed).

Conrad: "Fc epsilon RII/CD23: the low affinity receptor for IgE." dans: Annual review of immunology, Vol. 8, pp. 623-45, 1990 (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, 1979 (PubMed).

Avez-vous cherché autre chose?