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ITGA4 anticorps

ITGA4 Reactivité: Humain, Boeuf (Vache), Chien, Cheval, Cat, Mouton, Cynomolgus, Babouin, Macaque rhésus FACS Hôte: Souris Monoclonal 9F10 unconjugated
N° du produit ABIN2689306
  • Antigène Voir toutes ITGA4 Anticorps
    ITGA4 (Integrin alpha 4 (ITGA4))
    Reactivité
    • 140
    • 104
    • 36
    • 19
    • 14
    • 10
    • 9
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Boeuf (Vache), Chien, Cheval, Cat, Mouton, Cynomolgus, Babouin, Macaque rhésus
    Hôte
    • 81
    • 56
    • 48
    Souris
    Clonalité
    • 117
    • 70
    • 1
    Monoclonal
    Conjugué
    • 84
    • 18
    • 17
    • 14
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA4 est non-conjugé
    Application
    • 113
    • 62
    • 43
    • 40
    • 32
    • 25
    • 13
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marque
    BD Pharmingen™
    Attributs du produit
    Reaacts with the integrin α4 chain, which is expressed as a heterodimer with either of two β subunits, β1 (CD29) or β7. The α4β1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The α4β7 integrin has a similar tissue distribution, except it is found on only a small subpopulation of thymocytes. Integrin α4β7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression and function of a4 chain-containing integrins. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Mouse Anti-Human CD49d - Purified - Clone 9F10 - Isotype Mouse IgG1, κ - Reactivity Hu, Bab, Cat, Cow, Cyno, Dog, Hs, Rhe, Sheep - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    9F10
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGA4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Berlin, Berg, Briskin, Andrew, Kilshaw, Holzmann, Weissman, Hamann, Butcher: "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1." dans: Cell, Vol. 74, Issue 1, pp. 185-95, (1993) (PubMed).

    Parker, Cepek, Russell, Shaw, Posnett, Schwarting, Brenner: "A family of beta 7 integrins on human mucosal lymphocytes." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 5, pp. 1924-8, (1992) (PubMed).

    Hemler, Huang, Takada, Schwarz, Strominger, Clabby: "Characterization of the cell surface heterodimer VLA-4 and related peptides." dans: The Journal of biological chemistry, Vol. 262, Issue 24, pp. 11478-85, (1987) (PubMed).

  • Antigène
    ITGA4 (Integrin alpha 4 (ITGA4))
    Autre désignation
    CD49d (ITGA4 Produits)
    Synonymes
    anticorps CD49D, anticorps IA4, anticorps LOC100219853, anticorps integrin subunit alpha 4, anticorps integrin alpha 4, anticorps integrin subunit alpha 4 S homeolog, anticorps ITGA4, anticorps Itga4, anticorps itga4.S
    Sujet
    Synonyms: Integrin α4 chain
    Pathways
    Integrin Complex
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