IL10RA anticorps (Interleukin 10 Receptor, alpha)

Details for Product anti-IL10RA Antibody No. ABIN2689470
Antigène
  • IL10R1
  • IL10RA
  • CD210
  • CD210a
  • CDW210A
  • HIL-10R
  • IL-10R1
  • IL10R
  • AW553859
  • CDw210
  • CDw210a
  • Il10r
  • mIL-10R
  • interleukin 10 receptor subunit alpha
  • interleukin 10 receptor, alpha
  • IL10RA
  • Il10ra
Reactivité
Humain
162
49
24
2
2
1
1
1
1
Hôte
Rat
133
31
20
2
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp IL10RA est non-conjugé
13
9
6
4
4
4
4
4
4
4
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS)
112
55
36
27
24
13
12
6
6
5
3
2
1
1
Options
Marque BD Pharmingen™
Clone 3F9
Isotype IgG2a, kappa
Attributs du produit Reacts with 90-110 kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNγR (CDw119), IFNα/βR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages.

BD Pharmingen™ Purified Rat Anti-Human CDw210 - Purified - Clone 3F9 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others IL10RA products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation CDw210 (IL10RA Antibody Extrait)
Sujet Synonyms: IL-10 receptor
Pathways Growth Factor Binding
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 4°C.
Produit citée dans: Liu, de Waal Malefyt, Briere, Parham, Bridon, Banchereau, Moore, Xu: "The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 604-13, 1997 (PubMed).

Carson, Lindemann, Baiocchi, Linett, Tan, Chou, Narula, Caligiuri: "The functional characterization of interleukin-10 receptor expression on human natural killer cells." dans: Blood, Vol. 85, Issue 12, pp. 3577-85, 1995 (PubMed).

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