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TCR gamma/delta anticorps

TCR gamma/delta Reactivité: Souris FACS, IP, IHC (f) Hôte: Hamster arménien Monoclonal GL4 unconjugated
N° du produit ABIN2689921
  • Antigène Tous les produits TCR gamma/delta
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    Reactivité
    • 38
    • 24
    • 8
    • 8
    • 5
    • 4
    Souris
    Hôte
    • 40
    • 23
    • 16
    • 2
    Hamster arménien
    Clonalité
    • 81
    Monoclonal
    Conjugué
    • 23
    • 15
    • 13
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCR gamma/delta est non-conjugé
    Application
    • 73
    • 23
    • 18
    • 17
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Marque
    BD Pharmingen™
    Attributs du produit
    The GL4 antibody reacts with a common epitope of the δ chain of the γδ T-cell Receptor (TCR) complex on γδ TCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react with αβ TCR-bearing T cells. In the mouse, cells expressing the γδ TCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonary epithelium, peritoneum, liver, and peripheral lymphoid organs. Plate-bound GL4 antibody activates γδ TCR-bearing T cells.

    BD Pharmingen™ Purified Hamster Anti-Mouse TCR γδ - Purified - Clone GL4 - Isotype Armenian Hamster IgG2, κ - Reactivity Ms - 0.5 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    C57BL/6 mouse intestinal intraepithelial lymphocytes
    Clone
    GL4
    Isotype
    IgG2 kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • King, Hyde, Jackson, Novosad, Ellis, Putney, Stovall, Van Winkle, Beaman, Ferrick: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).

    Shinohara, Ikarashi, Maruoka, Miyata, Sugimura, Terada, Wakasugi: "Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains." dans: European journal of immunology, Vol. 29, Issue 6, pp. 1871-8, (1999) (PubMed).

    Tamaki, Yasaka, Chang, Ohtake, Saitoh, Nakamura, Furue: "Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin." dans: The Journal of investigative dermatology, Vol. 106, Issue 3, pp. 571-5, (1996) (PubMed).

    van der Heyde, Elloso, Chang, Kaplan, Manning, Weidanz: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).

    Kaufmann, Blum, Yamamoto: "Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 20, pp. 9620-4, (1993) (PubMed).

    Skeen, Ziegler: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." dans: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).

    Goodman, LeCorre, Lefrancois: "A T-cell receptor gamma delta-specific monoclonal antibody detects a V gamma 5 region polymorphism." dans: Immunogenetics, Vol. 35, Issue 1, pp. 65-8, (1992) (PubMed).

    Lefrancois: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).

    MacDonald, Schreyer, Howe, Bron: "Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells." dans: European journal of immunology, Vol. 20, Issue 4, pp. 927-30, (1990) (PubMed).

    Tigelaar, Lewis, Bergstresser: "TCR gamma/delta+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue." dans: The Journal of investigative dermatology, Vol. 94, Issue 6 Suppl, pp. 58S-63S, (1990) (PubMed).

    Goodman, Lefrancois: "Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function." dans: The Journal of experimental medicine, Vol. 170, Issue 5, pp. 1569-81, (1989) (PubMed).

  • Antigène
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    Autre désignation
    TCR Gammadelta (TCR gamma/delta Produits)
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